Puzzle 2008 04 014 Answer: Difference between revisions

The ECG in figure 1A shows sinus rhythm, an inter-mediate electrical axis, and a normal PQ interval and QRS duration. Furthermore, obvious ST-segmentelevation (STE) preceded by pathological Q waves inthe right precordial leads, STE in leads I and aVL, andreciprocal ST-segment depression in the inferior leads all imply an acute occlusion of the left anteriordescending (LAD) artery, located proximal to the firstseptal and first diagonal branch.<cite>Engelen</cite><cite>Tamura</cite> The recording in figure 1B reveals a regular rhythmwith broadened QRS complexes, likely a ventricular rhythm, of approximately 100 beats/min without visible atrial activation. The broadened QRS complexes(± 0.12 s) show a right bundle branch block (RBBB) configuration and a left anterior fascicular block, which causes the electrical axis to shift leftwards. Corrected QT intervals are normal. ST-segment shifts are com-parable to those in figure 1A. Both the left anterior fascicle and the right bundlebranch are supplied by septal branches of the proximal LAD artery.

Ischaemia-induced bifascicular block, defined as RBBB along with left anterior (or posterior) fascicular block, has been associated with a 30% excessrisk of complete heart block and should therefore be regarded as ‘bad news’. Additional prolongation of the PR interval, known as incomplete trifascicular block, is associated with imminent high-degree AV block and temporary or permanent pacing used to be recommended in these circumstances in the days prior toprimary PCI.<cite>Hindman</cite><cite>Antman</cite><cite>Gregoratos</cite>  

In the pre thrombolytic era, in-hospitalmortality in these patients could be as high as 80%,which was mainly related to an extensive loss offunctioning myocardium.<cite>Hindman2</cite> In an emergency situation, a brief evaluation of theECG depicted in figure 1B could lead to the mis-diagnosis of a multifascicular conduction block causedby acute occlusion of the LAD artery. Nevertheless,and in contrary to the ECG in figure 1A, a normal Pwave or other forms of atrial pacemaker activity areabsent in this recording. Finally, the ECG recorded justprior to emergency coronary angiography (figure 2)shows both electrocardiographic appearances. We see the transition from the regular ventricular rhythm intosinus rhythm with subsequent disappearance of RBBB configuration and left anterior fascicular block.