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Early Repolarization: Difference between revisions
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|yes | |yes | ||
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|Stavrakis | |Stavrakis<cite>17</cite> | ||
|2012, ANEC | |2012, ANEC | ||
|825ER, 255controls | |825ER, 255controls | ||
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A third outcome study, by Haruta et al. concluded that ER was only predictive of ''unexplained death''. Although ''unexplained death'' was intended to be a surrogate for cardiac arrest, the main category coded was unexplained accidental death. | A third outcome study, by Haruta et al. concluded that ER was only predictive of ''unexplained death''. Although ''unexplained death'' was intended to be a surrogate for cardiac arrest, the main category coded was unexplained accidental death. | ||
A fourth study by Stavrakis et al considered 852 consecutive patients with ST elevation ≥0.1 mV in inferior or lateral leads from the VA ECG system, similar to what we have used, and randomly selected 257 age-matched patients with normal ECGs as controls. | A fourth study by Stavrakis et al considered 852 consecutive patients with ST elevation ≥0.1 mV in inferior or lateral leads from the VA ECG system, similar to what we have used, and randomly selected 257 age-matched patients with normal ECGs as controls.<cite>17</cite> | ||
Early repolarization was associated with a modest increased mortality compared to controls (hazard ratio of 1.49), but comparison to controls rather than the total population from the sampling period of those with ER violates the assumptions of the Cox model. | Early repolarization was associated with a modest increased mortality compared to controls (hazard ratio of 1.49), but comparison to controls rather than the total population from the sampling period of those with ER violates the assumptions of the Cox model. | ||