Catecholaminergic Polymorphic Ventricular Tachycardia: Difference between revisions

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** the CASQ2 gene, coding for the calsequestrine protein: ([[w:OMIM|OMIM™]] link {{OMIM2|114251}}) (1-2 % of patients)
** the CASQ2 gene, coding for the calsequestrine protein: ([[w:OMIM|OMIM™]] link {{OMIM2|114251}}) (1-2 % of patients)


'''Treatment'''<cite>ACC2006</cite>
'''Treatment'''<cite>sumitomo</cite>
* Beta-blockers
* Beta-blockers
* [[w:nl:Internal_Cardiac_Defibrillator|ICD]] implantation combined with beta-blockers in CPVT patients who survived a cardiac arrest or patients with syncope and/or documented sustained [[Ventricular Tachycardia|ventricular tachycardia]] despite beta-blocker therapy.<cite>sumitomo</cite>  
* [[w:nl:Internal_Cardiac_Defibrillator|ICD]] implantation combined with beta-blockers in CPVT patients who survived a cardiac arrest or patients with syncope and/or documented sustained [[Ventricular Tachycardia|ventricular tachycardia]] despite beta-blocker therapy.<cite>ACC2006</cite>  
* Surgical left cardiac sympathetic denervation in selected patients whose symptoms and/or ventricular arrhythmias are not controlled by pharmacologic therapy (Wilde, NEJM, 2009; Collura, Heart Rhythm, 2009)
* Surgical left cardiac sympathetic denervation in selected patients whose symptoms and/or ventricular arrhythmias are not controlled by pharmacologic therapy <cite>Wilde</cite><cite>Collura</cite>
* Avoid competitive and other strenuous exercise
* Avoid competitive and other strenuous exercise


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#ACC2006 pmid=16935995
#ACC2006 pmid=16935995
#sumitomo pmid=12482795
#sumitomo pmid=12482795
#Wilde pmid=18463378
#Collura pmid=19467503
</biblio>
</biblio>

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