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The '''Long QT Syndrome (LQTS)''' is characterized on the ECG by prolongation of the [[Conduction#The_QT_interval|heart rate corrected QT interval]]. This was first recognized by Dr. Jervell and Dr. Lange-Nielsen in 1957. They described 4 children with a long QT interval which was accompanied by hearing deficits, sudden cardiac death and an autosomal recessive inheritance.<cite>Lang1957</cite> | |||
The '''Long QT Syndrome (LQTS)''' is characterized on the ECG by prolongation of the [[Conduction#The_QT_interval|heart rate corrected QT interval]]. This was first recognized by | |||
The Long QT syndrome may be divided into two distinct forms: congenital Long QT syndrome and acquired Long QT syndrome. These forms may however overlap when QT prolongation due to medication occurs in a patient with congenital Long QT syndrome. | The Long QT syndrome may be divided into two distinct forms: congenital Long QT syndrome and acquired Long QT syndrome. These forms may however overlap when QT prolongation due to medication occurs in a patient with congenital Long QT syndrome. | ||
<gallery> | |||
File:acquired_longQT.jpg|A 12-lead ECG of a patient with acquired long QT syndrome. Notice the QT prolongation. The QTc is about 640ms. | |||
File:Lqts1.png|A 12 lead ECG of a patient with genetically proven LQTS1 | |||
File:Lqts2.png|A 12 lead ECG of a patient with genetically proven LQTS2 | |||
File:Lqts3.png|A 12 lead ECG of a patient with genetically proven LQTS3 | |||
</gallery> | |||
===Diagnosis=== | ===Diagnosis=== | ||
*The diagnosis is by measurement of the [[Conduction#The_QT_interval|heart rate-corrected QT interval]] on the ECG, which can be calculated with the [[QTc calculator]]. | *The diagnosis is by measurement of the [[Conduction#The_QT_interval|heart rate-corrected QT interval]] on the ECG, which can be calculated with the [[QTc calculator]]. | ||
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#moss pmid=17470695 | #moss pmid=17470695 | ||
#priori pmid=12736279 | #priori pmid=12736279 | ||
#Hofman pmid= | #Hofman pmid=17090615 | ||
#Roden pmid=18184962 | #Roden pmid=18184962 | ||
</biblio> | </biblio> |