Short QT Syndrome: Difference between revisions
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There is controversy whether short QT intervals are associated with sudden death. One trial found QTc intervals < 300ms to be associated with sudden death.<cite>Gaita</cite> However, a recent Finnish study in a random selection of healthy subjects (n=10 822) did not find an increased incidence of sudden death in patients with short QTc intervals. They defined QTc < 320ms as 'very short' and QTc < 340ms as 'short'. In total, 15 deaths occured in the group with QTc <340ms, with only one possible sudden death (cause of death unknown). They used Friderica's method for QTc correction: [[Image:Fridericia.png|100px]].<cite>Fridericia</cite> They conclude that the ECG is not a good screening tool to find patients with a short QTc interval at risk of sudden death.<cite>Anttonen</cite> | There is controversy whether short QT intervals are associated with sudden death. One trial found QTc intervals < 300ms to be associated with sudden death.<cite>Gaita</cite> However, a recent Finnish study in a random selection of healthy subjects (n=10 822) did not find an increased incidence of sudden death in patients with short QTc intervals. They defined QTc < 320ms as 'very short' and QTc < 340ms as 'short'. In total, 15 deaths occured in the group with QTc <340ms, with only one possible sudden death (cause of death unknown). They used Friderica's method for QTc correction: [[Image:Fridericia.png|100px]].<cite>Fridericia</cite> They conclude that the ECG is not a good screening tool to find patients with a short QTc interval at risk of sudden death.<cite>Anttonen</cite> | ||
[[File: | [[File:Sqts.svg|thumb|Precordial ECG tracings of a patient with SQTS]] | ||
== References == | == References == | ||
<biblio> | <biblio> | ||
Latest revision as of 13:33, 14 February 2010
There is controversy whether short QT intervals are associated with sudden death. One trial found QTc intervals < 300ms to be associated with sudden death.Gaita However, a recent Finnish study in a random selection of healthy subjects (n=10 822) did not find an increased incidence of sudden death in patients with short QTc intervals. They defined QTc < 320ms as 'very short' and QTc < 340ms as 'short'. In total, 15 deaths occured in the group with QTc <340ms, with only one possible sudden death (cause of death unknown). They used Friderica's method for QTc correction: 
.Fridericia They conclude that the ECG is not a good screening tool to find patients with a short QTc interval at risk of sudden death.Anttonen
References
<biblio>
- bazett Bazett HC. An analysis of the time-relations of electrocardiograms. Heart 1920;7:353-370.
- Lepeschkin pmid=14954534
- Gaita pmid=12925462
- Anttonen pmid=17679619
- Fridericia Fridericia LS. Die Systolendauer im Elektrokardiogramm bei normalen
Menschen und bei Herzkranken. Acta Med Scand. 1920;53:469–486. </biblio>