Early Repolarization: Difference between revisions

Characterization of standard 12 lead ECG abnormalities can be facilitated by considering the portion of the cardiac ventricular myocytes action potential which influences them. This is only helpful for action potential phenomena originating with the initial wave of activation. Their temporal timing is influenced mainly by transmural dispersion from endo to epicardium. This contrasts with late potentials which are due to phase 0 of the action potentials (depolarization) originating from myocardium isolated by fatty tissue (epsilon waves of ARVD) or by fibrosis (cardiomyopathy) experiencing major delays. These can be arrhythmogenic because they compete with the normal pacemakers.  

Phase 0 depolarization abnormalities that occur with the initial wave of activation include bundle branch blocks, myocardium damage or abnormalities and intraventicular delays. These can be due to electrical disturbances, myocardial hypertrophy, dilatation, damage or infiltrative disease.