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Clinical Disorders: Difference between revisions
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===Digoxin=== | ===Digoxin=== | ||
[[Image:med_digitalis.png|thumb|300px|Typical for digoxin intoxication is the oddly shaped ST-depression]] | [[Image:med_digitalis.png|thumb|300px|Typical for digoxin intoxication is the oddly shaped ST-depression]] | ||
ECG changes typical for digoxin | ECG changes typical for digoxin '''use''' (digoxin = Lanoxin) are: | ||
*Oddly shaped ST-depression | *Oddly shaped ST-depression with 'scooped out' appearance of the ST segment (see figure) | ||
* | *Flat, negative or biphasic T wave | ||
*Short QT interval | *Short QT interval | ||
*Increased u-wave amplitude | *Increased u-wave amplitude | ||
*Prolonged PR-interval | *Prolonged PR-interval | ||
*Sinus bradycardia | |||
ECG changes typical for digoxin '''intoxication''' are: | |||
*Bradyarrhythmias: | *Bradyarrhythmias: | ||
**AV block. Including complete AV block and Wenkebach. | **AV block. Including complete AV block and Wenkebach. | ||
*Tachyarrhythmias: | *Tachyarrhythmias: | ||
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Intoxication can lead to an SA-block or AV-block, sometimes in combination with tachycardia. '''NB''' these effects are increased by hypokalemia. In extreme high concentrations rhythm disturbances (''ventricular tachycardia, ventricular fibrillation, atrial fibrillation'') may develop. | Intoxication can lead to an SA-block or AV-block, sometimes in combination with tachycardia. '''NB''' these effects are increased by hypokalemia. In extreme high concentrations rhythm disturbances (''ventricular tachycardia, ventricular fibrillation, atrial fibrillation'') may develop. | ||
{{clr}} | {{clr}} | ||
===Antiarrhythmics=== | ===Antiarrhythmics=== | ||
* '''Anti-arrhythmics:''' These may lead to several ECG-changes; | * '''Anti-arrhythmics:''' These may lead to several ECG-changes; | ||