Repolarization (ST-T,U) Abnormalities

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Author(s) I.A.C. van der Bilt
Moderator I.A.C. van der Bilt
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Repolarization can be influenced by many factors, including electrolyte shifts, ischemia, structural heart disease (cardiomyopathy) and (recent) arrhythmias. Although T/U wave abnormalities are rarely specific for one disease, it can be useful to know which conditions can change repolarization.

Early repolarization is a normal variant of the ST segment, seen in 2-5% of patients, especially young men. Early repolarization is characterized by elevation of the J point and the beginning of the ST segment as well as elevation of the ST segment itself[1]. The ST segment may be concave up (cup-like) or concave (dome-like). These findings are most often present in the middle chest leads V2-V5. Recently a different form of early repolarization has been associated with idiopathic ventricular fibrillation. This form is most often seen in lead II and consists of a 'hump' in the tail of the QRS complex, without ST elevation.

[edit] References

  1. Wellens HJ. Early repolarization revisited. N Engl J Med 2008 May 8; 358(19) 2063-5. doi:10.1056/NEJMe0801060 pmid:18463384. PubMed HubMed [Wellens]
  2. Tikkanen JT, Anttonen O, Junttila MJ, Aro AL, Kerola T, Rissanen HA, Reunanen A, and Huikuri HV. Long-term outcome associated with early repolarization on electrocardiography. N Engl J Med 2009 Dec 24; 361(26) 2529-37. doi:10.1056/NEJMoa0907589 pmid:19917913. PubMed HubMed [Tikkanen]
All Medline abstracts: PubMed HubMed
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