4,199
edits
Long QT Syndrome: Difference between revisions
m
→Aangeboren LQTS
mNo edit summary |
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| Line 30: | Line 30: | ||
| chromosoom | | chromosoom | ||
| gen (met [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM OMIM] links) | | gen (met [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM OMIM] links) | ||
| | | protein | ||
| ionchannel | |||
| frequentie | | frequentie | ||
| SCD incidentie | | SCD incidentie | ||
| Line 41: | Line 42: | ||
| 11p15 | | 11p15 | ||
| [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607542&rn=1 KCNQ1] | | [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607542&rn=1 KCNQ1] | ||
| KvLQT1 | | KvLQT1 | ||
| I''ks'' | |||
| ~50% | | ~50% | ||
| 0.30%/jaar | | 0.30%/jaar | ||
| Line 52: | Line 54: | ||
| 7q35 | | 7q35 | ||
| [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=152427 KCNH2] | | [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=152427 KCNH2] | ||
| hERG | | hERG | ||
| I''kr'' | |||
| 30-40% | | 30-40% | ||
| 0.60%/jaar | | 0.60%/jaar | ||
| Line 64: | Line 67: | ||
| [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 SCN5A] | | [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 SCN5A] | ||
| NA kanaal | | NA kanaal | ||
| | |||
| 5-10% | | 5-10% | ||
| 0.56%/jaar | | 0.56%/jaar | ||
| Line 75: | Line 79: | ||
| [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106410 ANK2] | | [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106410 ANK2] | ||
| Ankyrin B | | Ankyrin B | ||
| | |||
| <1% | | <1% | ||
| | | | ||
| Line 85: | Line 90: | ||
| 21q22 | | 21q22 | ||
| [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176261 KCNE1] | | [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176261 KCNE1] | ||
| minK | | minK | ||
| I''ks'' | |||
| <1% | | <1% | ||
| | | | ||
| Line 96: | Line 102: | ||
| 21q22 | | 21q22 | ||
| [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603796 KCNE2] | | [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603796 KCNE2] | ||
| MiRP1 | | MiRP1 | ||
| I''kr'' | |||
| <1% | | <1% | ||
| | | | ||
| Line 107: | Line 114: | ||
| 17q23 | | 17q23 | ||
| [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600681 KCNJ2] | | [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600681 KCNJ2] | ||
| Kir 2.1 | | Kir 2.1 | ||
| I''K1'' | |||
| <1% | | <1% | ||
| | | | ||
| Line 118: | Line 126: | ||
| 6q8A | | 6q8A | ||
| [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=114205 CACNA1C] | | [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=114205 CACNA1C] | ||
| | | | ||
| I''Ca-L'' | |||
| <1% | | <1% | ||
| | | | ||