Long QT Syndrome: Difference between revisions

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m (New page: Conclusions—This genotype–phenotype study indicates that in type-1 LQTS, mutations located in the transmembrane portion of the ion channel protein and the degree of ion channel dysfu...)
 
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Conclusions—This genotype–phenotype study indicates that in type-1 LQTS, mutations located in the transmembrane
Conclusions—This genotype–phenotype study indicates that in type-1 LQTS, mutations located in the transmembrane
portion of the ion channel protein and the degree of ion channel dysfunction caused by the mutations are important
portion of the ion channel protein and the degree of ion channel dysfunction caused by the mutations are important
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===References===
===References===
<biblio>
<biblio>
moss pmid=17470695
</biblio>
</biblio>

Revision as of 08:02, 15 May 2007

Conclusions—This genotype–phenotype study indicates that in type-1 LQTS, mutations located in the transmembrane portion of the ion channel protein and the degree of ion channel dysfunction caused by the mutations are important independent risk factors influencing the clinical course of this disorder.[1]

References

  1. Moss AJ, Shimizu W, Wilde AA, Towbin JA, Zareba W, Robinson JL, Qi M, Vincent GM, Ackerman MJ, Kaufman ES, Hofman N, Seth R, Kamakura S, Miyamoto Y, Goldenberg I, Andrews ML, and McNitt S. Clinical aspects of type-1 long-QT syndrome by location, coding type, and biophysical function of mutations involving the KCNQ1 gene. Circulation. 2007 May 15;115(19):2481-9. DOI:10.1161/CIRCULATIONAHA.106.665406 | PubMed ID:17470695 | HubMed [moss]