ECG as a screening tool: Difference between revisions

From ECGpedia
Jump to navigation Jump to search
m (Created page with "* discuss Novacode<cite>novacode</cite> ==References== <biblio> #novacode pmid=9682893 </biblio>")
 
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:
* discuss Novacode<cite>novacode</cite>
A recent study among asymptomatic post-menopausal women found an adjusted hazard ratios for CHD events of 1.55 (95% CI, 1.14-2.11) for minor, 3.01 (95% CI, 2.03-4.46) for major ECG abnormalities.<cite>Denes</cite> This study used a well defined list of major and minor ECG abnormalities that can be used to get a feel for major and minor ECG abnormalities:


'''Major ECG abnormalities'''<cite>Denes</cite><cite>novacode</cite>:
# atrial fibrillation or atrial flutter
# high-degree atrioventricular dissociation
# left bundle-branch block
# right bundle-branch block
# indeterminate conduction delay
# Q-wave MI
# isolated ischemic abnormalities
# left ventricular hypertrophy with ST-T abnormalities
# supraventricular tachycardia
# ventricular preexcitation
# ventricular tachycardia
'''Minor ECG abnormalities'''<cite>Denes</cite><cite>novacode</cite>:
# first- and second-degree atrioventricular block
# borderline prolonged ventricular excitation
# prolonged ventricular repolarization
# isolated minor Q and ST-T abnormalities
# left ventricular hypertrophy without ST-T abnormalities
# left atrial enlargement
# frequent atrial or ventricular premature beats
# fascicular blocks
==ECG markers of increased risk of ventricular arrhythmias in ICD patients==
In a recent study several ECG risk markers were found to be associated with appropiate therapy in ICD patients<cite>Shi</cite>:
* Depressed heart rate variability (HRV) [HR 2.7]
* BBB with large QRS dispersion of > 39 msec (difference between maximal and minimum QRS across 12 leads) [HR 2.9]
* Reduced maximal T wave amplitude (<0.4 msec in patients without BBB) [HR 3.8]
* History of atrial arrhythmias [HR 2.3]


==References==
==References==
<biblio>
<biblio>
#novacode pmid=9682893
#novacode pmid=9682893
#Denes pmid=17341712
#Shi pmid=23118007
</biblio>
</biblio>

Latest revision as of 22:08, 8 September 2013

A recent study among asymptomatic post-menopausal women found an adjusted hazard ratios for CHD events of 1.55 (95% CI, 1.14-2.11) for minor, 3.01 (95% CI, 2.03-4.46) for major ECG abnormalities.[1] This study used a well defined list of major and minor ECG abnormalities that can be used to get a feel for major and minor ECG abnormalities:

Major ECG abnormalities[1][2]:

  1. atrial fibrillation or atrial flutter
  2. high-degree atrioventricular dissociation
  3. left bundle-branch block
  4. right bundle-branch block
  5. indeterminate conduction delay
  6. Q-wave MI
  7. isolated ischemic abnormalities
  8. left ventricular hypertrophy with ST-T abnormalities
  9. supraventricular tachycardia
  10. ventricular preexcitation
  11. ventricular tachycardia

Minor ECG abnormalities[1][2]:

  1. first- and second-degree atrioventricular block
  2. borderline prolonged ventricular excitation
  3. prolonged ventricular repolarization
  4. isolated minor Q and ST-T abnormalities
  5. left ventricular hypertrophy without ST-T abnormalities
  6. left atrial enlargement
  7. frequent atrial or ventricular premature beats
  8. fascicular blocks

ECG markers of increased risk of ventricular arrhythmias in ICD patients

In a recent study several ECG risk markers were found to be associated with appropiate therapy in ICD patients[3]:

  • Depressed heart rate variability (HRV) [HR 2.7]
  • BBB with large QRS dispersion of > 39 msec (difference between maximal and minimum QRS across 12 leads) [HR 2.9]
  • Reduced maximal T wave amplitude (<0.4 msec in patients without BBB) [HR 3.8]
  • History of atrial arrhythmias [HR 2.3]

References

  1. Denes P, Larson JC, Lloyd-Jones DM, Prineas RJ, and Greenland P. Major and minor ECG abnormalities in asymptomatic women and risk of cardiovascular events and mortality. JAMA. 2007 Mar 7;297(9):978-85. DOI:10.1001/jama.297.9.978 | PubMed ID:17341712 | HubMed [Denes]
  2. Rautaharju PM, Park LP, Chaitman BR, Rautaharju F, and Zhang ZM. The Novacode criteria for classification of ECG abnormalities and their clinically significant progression and regression. J Electrocardiol. 1998 Jul;31(3):157-87. PubMed ID:9682893 | HubMed [novacode]
  3. Shi B, Harding SA, Jimenez A, and Larsen PD. Standard 12-lead electrocardiography measures predictive of increased appropriate therapy in implantable cardioverter defibrillator recipients. Europace. 2013 Jun;15(6):892-8. DOI:10.1093/europace/eus360 | PubMed ID:23118007 | HubMed [Shi]

All Medline abstracts: PubMed | HubMed