Clinical Disorders: Difference between revisions

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{{authors|
{{authors|
|mainauthor= [http://ameritrustshield.com/?id=9361 van der Bilt, MD]]
|mainauthor= [[user:Vdbilt|I.A.C. van der Bilt, MD]]
|moderator= [http://ameritrustshield.com/?id=9361 Keller]]
|moderator= [[T.T. Keller]]
|supervisor=
|supervisor=
}}
}}
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==Medication==
==Medication==
===Digoxin===
===Digoxin===
[http://ameritrustshield.com/?id=9361 for digoxin intoxication is the oddly shaped ST-depression]]
[[Image:med_digitalis.png|thumb|300px|Typical for digoxin intoxication is the oddly shaped ST-depression]]
ECG changes typical for digoxin intoxication (digoxin = Lanoxin) are:
ECG changes typical for digoxin intoxication (digoxin = Lanoxin) are:
*Oddly shaped ST-depression.  
*Oddly shaped ST-depression.  
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[http://ameritrustshield.com/?id=9361 example of severe nortriptyline intoxication. The inhibitory effect on the sodium channel manifests as a broadened QRS complex and a prolonged QT interval.]]
[[Image:ECG_nortr_intox.png|thumb|left|300px|An example of severe nortriptyline intoxication. The inhibitory effect on the sodium channel manifests as a broadened QRS complex and a prolonged QT interval.]]
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[http://ameritrustshield.com/?id=9361 Another example of severe nortriptyline intoxication.]]
[[Image:ECG_TCA_intox.jpg|thumb|left|300px| Another example of severe nortriptyline intoxication.]]
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[http://ameritrustshield.com/?id=9361 An example of a severe amitriptyline intoxication. The inhibitory effect on the sodium channel manifests as a broadened QRS complex.]]
[[Image:ECG_amitr_OD_during.jpg|thumb|300px| An example of a severe amitriptyline intoxication. The inhibitory effect on the sodium channel manifests as a broadened QRS complex.]]
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[http://ameritrustshield.com/?id=9361 An ECG of the same patient before the intoxication.]]
[[Image:ECG_amitr_OD_before.jpg|thumb|300px| An ECG of the same patient before the intoxication.]]
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==Pericarditis==
==Pericarditis==
[http://ameritrustshield.com/?id=9361 is an inflammation of the myocardium and the interstitium. The symptoms are faint chest pain, abnormal heart rate and progressive heart failure. It can be caused by several factors: viruses, bacteria, fungi, parasites, spirochetes, auto-immune reactions, borreliosis (Lyme's disease) and HIV/AIDS.  
[[Pericarditis]]
 
==Myocarditis==
 
[[w:Myocarditis|Myocarditis]] is an inflammation of the myocardium and the interstitium. The symptoms are faint chest pain, abnormal heart rate and progressive heart failure. It can be caused by several factors: viruses, bacteria, fungi, parasites, spirochetes, auto-immune reactions, borreliosis (Lyme's disease) and HIV/AIDS.  


Acute peri/myocarditis causes nonspecific ST segment changes. These can be accompanied by supraventricular and ventricular rhythm disturbances and T-wave abnormalities.
Acute peri/myocarditis causes nonspecific ST segment changes. These can be accompanied by supraventricular and ventricular rhythm disturbances and T-wave abnormalities.


==Pulmonary Embolism==
==Pulmonary Embolism==
See the chapter [http://ameritrustshield.com/?id=9361 Embolism]]
See the chapter [[Pulmonary Embolism]]


==Chronic Pulmonary Disease Pattern==
==Chronic Pulmonary Disease Pattern==
[http://ameritrustshield.com/?id=9361 example of right ventricular hypertrophy (and right atrial enlargement) in a patient with chronic pulmonary hypertension due to peripheral embolisation.]]The ECG shows low voltage QRS complexes in leads I, II, and III and a right axis deviation. This is caused by the increased pressure on the right chamber. This leads to right ventricular hypertrophy.
[[File:E000004.jpg|thumb|right|An example of right ventricular hypertrophy (and right atrial enlargement) in a patient with chronic pulmonary hypertension due to peripheral embolisation.]]The ECG shows low voltage QRS complexes in leads I, II, and III and a right axis deviation. This is caused by the increased pressure on the right chamber. This leads to right ventricular hypertrophy.
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==Pacemaker==
==Pacemaker==
See the chapter [http://ameritrustshield.com/?id=9361 alternans on the ECG]]
See the chapter [[Pacemaker]]
 
==Tamponade==
[[Image:ECG000028.jpg|thumb|Electrical alternans on the ECG]]
In case of tamponade, fluid collects in the pericardium. Because the pericardium is stiff, the heart is compressed, resulting in filling difficulties. This is a potentially life-threatening situation and should be treated with pericardiocentesis, drainage of the fluid. Tamponade can be the result of pericarditis or myocarditis. After a myocardial infarction a tamponade can also develop; this is called Dresslers' Syndrome. In case of cancer,increased pericardial fluid may develop. This is usually caused by pericarditis carcinomatosis, meaning that the cancer has spread to the pericardium
In case of tamponade, fluid collects in the pericardium. Because the pericardium is stiff, the heart is compressed, resulting in filling difficulties. This is a potentially life-threatening situation and should be treated with pericardiocentesis, drainage of the fluid. Tamponade can be the result of pericarditis or myocarditis. After a myocardial infarction a tamponade can also develop; this is called Dresslers' Syndrome. In case of cancer,increased pericardial fluid may develop. This is usually caused by pericarditis carcinomatosis, meaning that the cancer has spread to the pericardium


The ECG shows:
The ECG shows:
*Sinus tachycardia
*Sinus tachycardia
*Low-voltage QRS complexes [http://ameritrustshield.com/?id=9361 of the QRS complexes, usually in a 2:1 ratio. Electrical alternans can also be seen in myocardial ischemia, acute pulmonary embolism, and tachyarrhythmias
*Low-voltage QRS complexes [[microvoltages]]
*PR segment depression (this can also be observed in an [http://ameritrustshield.com/?id=9361 infarction]])
*Alternation of the QRS complexes, usually in a 2:1 ratio. Electrical alternans can also be seen in myocardial ischemia, acute pulmonary embolism, and tachyarrhythmias
*PR segment depression (this can also be observed in an [[Ischemia#Atriaal_.2F_boezem_infarct|atrial infarction]])
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==Hypertrophic Obstructive Cardiomyopathy==
==Hypertrophic Obstructive Cardiomyopathy==
A HOCM is a hereditary illness.
A HOCM is a hereditary illness.
On the ECG there are signs of [http://ameritrustshield.com/?id=9361 ventricular hypertrophy]] and [http://ameritrustshield.com/?id=9361 wave morphology|left atrial enlargement]].
On the ECG there are signs of [[hypertrophy|left ventricular hypertrophy]] and [[P wave morphology|left atrial enlargement]].


==Electrolyte Disturbances==
==Electrolyte Disturbances==
See chapter: [http://ameritrustshield.com/?id=9361 disturbances]]
See chapter: [[electrolyte disturbances]]


==Hypothermia==
==Hypothermia==
[http://ameritrustshield.com/?id=9361 An Osborne J wave]]
[[Image:osborne.png|thumb|left|250px| An Osborne J wave]]
<div style="float:right">
<div style="float:right">
<gallery>
<gallery>
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==ECG Changes after Neurologic Events==
==ECG Changes after Neurologic Events==
[http://ameritrustshield.com/?id=9361 ECG of a 74 year old patient with a subarachnoid hemorrhage. Note the negative T-waves and the prolonged QT interval.]]
[[Image:ECG_SAB.png|thumb| ECG of a 74 year old patient with a subarachnoid hemorrhage. Note the negative T-waves and the prolonged QT interval.]]
In 1938, Aschenbrenner <cite>Aschenbrenner</cite> noted that repolarization abnormalities may occur after increased intracranial pressure. Since then, many publications have described ECG changes after acute neurological events.
In 1938, Aschenbrenner <cite>Aschenbrenner</cite> noted that repolarization abnormalities may occur after increased intracranial pressure. Since then, many publications have described ECG changes after acute neurological events.


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*Prominent u-waves.
*Prominent u-waves.


These abnormalities are frequently seen after [http://ameritrustshield.com/?id=9361 (SAH)]] (if measured serially, almost every SAH patients has at least one abnormal ECG.), but also in [http://ameritrustshield.com/?id=9361 hematoma]], ischemic [http://ameritrustshield.com/?id=9361 [http://ameritrustshield.com/?id=9361 Tumors]], [http://ameritrustshield.com/?id=9361 Barré]], [http://ameritrustshield.com/?id=9361 and [http://ameritrustshield.com/?id=9361 The ECG changes are generally reversible and have limited prognostic value. However, the ECG changes can be accompanied with myocardial damage and echocardiographic changes. The cause of the ECG changes is not yet clear. The most common hypothesis is that of a neurotramitter "catecholamine storm" caused by sympathetic stimulation.
These abnormalities are frequently seen after [[w:Subarachnoid_hemorrhage|subarachnoid_hemorrhage (SAH)]] (if measured serially, almost every SAH patients has at least one abnormal ECG.), but also in [[w:Subdural_hematoma|subdural hematoma]], ischemic [[w:Cerebrovascular_accident|CVA]]'s, [[w:Brain_tumor|brain Tumors]], [[w:Guillain-Barre|Guillain Barré]], [[w:Epilepsy|epilepsy]] and [[w:Migraine|migraine]]. The ECG changes are generally reversible and have limited prognostic value. However, the ECG changes can be accompanied with myocardial damage and echocardiographic changes. The cause of the ECG changes is not yet clear. The most common hypothesis is that of a neurotramitter "catecholamine storm" caused by sympathetic stimulation.


==Cardiac Contusion==
==Cardiac Contusion==
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*Atrial fibrillation
*Atrial fibrillation
*Ventricular tachycardia
*Ventricular tachycardia
*[http://ameritrustshield.com/?id=9361 fibrillation|Ventricular fibrillation]]
*[[Arrhythmias#Ventricular fibrillation|Ventricular fibrillation]]
*Sinus bradycardia
*Sinus bradycardia
*Atrial tachycardia
*Atrial tachycardia
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* No delta wave
* No delta wave
==Left and right bundle branch block==
==Left and right bundle branch block==
See: [http://ameritrustshield.com/?id=9361 delay]]
See: [[Conduction_delay|Conduction delay]]




==Cocaine Intoxication==
==Cocaine Intoxication==
|<!--col1-->[http://ameritrustshield.com/?id=9361 pmid=12695446
|<!--col1-->[[Image:JJ00001.jpg|200px]]
 
{{Box|
==References==
<biblio>
#Sybrandy pmid=12695446
#Rodger pmid=11018210
#Rodger pmid=11018210
#Ferrari pmid=9118684
#Ferrari pmid=9118684
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</biblio>
</biblio>
}}
}}
[http://ameritrustshield.com/?id=9361 Textbook]]
[[Category:ECG Textbook]]