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Action potential - Revision history
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Drj: /* Een Actiepotentiaal */
2008-09-07T21:31:48Z
<p><span dir="auto"><span class="autocomment">Een Actiepotentiaal</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 21:31, 7 September 2008</td>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">== Een Actiepotentiaal ==</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">An individual cardiomyocyte contracts when </ins>calcium <ins style="font-weight: bold; text-decoration: none;">ions enter the cell</ins>. <ins style="font-weight: bold; text-decoration: none;">These </ins>calcium <ins style="font-weight: bold; text-decoration: none;">ions must also be transported out of the cell to prevent calcium overload</ins>. <ins style="font-weight: bold; text-decoration: none;">Each heartbeat ions enter and exit the cell through </ins>ion <ins style="font-weight: bold; text-decoration: none;">channels in the cell membrane</ins>. </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Een individuele hartcel spant zich aan wanneer er </del>calcium<del style="font-weight: bold; text-decoration: none;">-ionen naar binnen stromen</del>. <del style="font-weight: bold; text-decoration: none;">Maar deze </del>calcium<del style="font-weight: bold; text-decoration: none;">-ionen moeten ook weer naar buiten, anders zou de cel aangespannen blijven</del>. <del style="font-weight: bold; text-decoration: none;">Iedere hartslag opnieuw worden er ionen naar binnen gelaten en weer naar buiten gepompt door </del>ion<del style="font-weight: bold; text-decoration: none;">-kanalen op de hartspiercel</del>.</div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Dit proces wordt </del>in <del style="font-weight: bold; text-decoration: none;">gang gezet door een doorgegeven electrisch signaal van de naburige cellen</del>. <del style="font-weight: bold; text-decoration: none;">Als reactie hierop</del>, <del style="font-weight: bold; text-decoration: none;">depolariseert de hartcel</del>. <del style="font-weight: bold; text-decoration: none;">Hierbij maakt hij ook zelf een electrisch signaal</del>, <del style="font-weight: bold; text-decoration: none;">de actiepotentiaal</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">This process is put </ins>in <ins style="font-weight: bold; text-decoration: none;">motion by an electrical signal transmitted from the neighboring cells</ins>. <ins style="font-weight: bold; text-decoration: none;">In response</ins>, <ins style="font-weight: bold; text-decoration: none;">the cardiomyocyte depolarizes</ins>. <ins style="font-weight: bold; text-decoration: none;">In doing so it also makes it's own electrical signal</ins>, <ins style="font-weight: bold; text-decoration: none;">the action potential</ins>.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Deze actiepotentiaal bestaat uit een aantal fasen</del>;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">This action potential entails a number of phases</ins>;</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>*'''<del style="font-weight: bold; text-decoration: none;">Fase </del>4''', <del style="font-weight: bold; text-decoration: none;">ook wel de rustfase</del>. <del style="font-weight: bold; text-decoration: none;">Het membraanpotentiaal; </del>-90mV</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>*'''<ins style="font-weight: bold; text-decoration: none;">Phase </ins>4''', <ins style="font-weight: bold; text-decoration: none;">also known as the resting phase</ins>. <ins style="font-weight: bold; text-decoration: none;">The membrane potential is at </ins>-90mV</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>*'''<del style="font-weight: bold; text-decoration: none;">Fase </del>0'''<del style="font-weight: bold; text-decoration: none;">, Snelle natrium kanalen worden geopend en natrium stroomt de cel in </del>(<del style="font-weight: bold; text-decoration: none;">depolarisatie</del>). <del style="font-weight: bold; text-decoration: none;">Dit zorgt voor de snelle </del>upstroke.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>*'''<ins style="font-weight: bold; text-decoration: none;">Phase </ins>0''' <ins style="font-weight: bold; text-decoration: none;">fast sodium channels open and sodium flows into the cell </ins>(<ins style="font-weight: bold; text-decoration: none;">depolarises</ins>). <ins style="font-weight: bold; text-decoration: none;">This results in the rapid </ins>upstroke.</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>*'''<del style="font-weight: bold; text-decoration: none;">Fase </del>1''', <del style="font-weight: bold; text-decoration: none;">Kalium stroomt de cel uit </del>(efflux) <del style="font-weight: bold; text-decoration: none;">wat ervoor zorgt dat het membraanpotentiaal zichzelf herstelt naar </del>0mV</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>*'''<ins style="font-weight: bold; text-decoration: none;">Phase </ins>1''', <ins style="font-weight: bold; text-decoration: none;">potassium flows from the cell </ins>(efflux) <ins style="font-weight: bold; text-decoration: none;">which increases the membrane potential restores to </ins>0mV</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>*'''<del style="font-weight: bold; text-decoration: none;">Fase </del>2''', <del style="font-weight: bold; text-decoration: none;">ook wel de plateaufase Deze fase wordt gekenmerkt door kalium </del>efflux <del style="font-weight: bold; text-decoration: none;">en calicium </del>influx <del style="font-weight: bold; text-decoration: none;">(de cel in)</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>*'''<ins style="font-weight: bold; text-decoration: none;">Phase </ins>2''', <ins style="font-weight: bold; text-decoration: none;">also known as the plateau phase. This phase is characterized by potassium </ins>efflux <ins style="font-weight: bold; text-decoration: none;">and calcium </ins>influx.</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>*'''<del style="font-weight: bold; text-decoration: none;">Fase </del>3''', <del style="font-weight: bold; text-decoration: none;">De kalium </del>efflux <del style="font-weight: bold; text-decoration: none;">overschrijdt de </del>calcium influx. <del style="font-weight: bold; text-decoration: none;">De membraanpotentiaal herstelt zich weer tot </del>90mV (<del style="font-weight: bold; text-decoration: none;">repolarisatie</del>).</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>*'''<ins style="font-weight: bold; text-decoration: none;">Phase </ins>3''', <ins style="font-weight: bold; text-decoration: none;">the potassium </ins>efflux <ins style="font-weight: bold; text-decoration: none;">exceeds the </ins>calcium influx. <ins style="font-weight: bold; text-decoration: none;">The membrane potential decreases to </ins>90mV (<ins style="font-weight: bold; text-decoration: none;">repolarization</ins>).</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Image:actionpotential.png|thumb|<del style="font-weight: bold; text-decoration: none;">De actiepotentiaal van een cardiomyocyt kent verschillende fasen en bijbehordende ionstromen</del>.]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Image:actionpotential.png | thumb | <ins style="font-weight: bold; text-decoration: none;">The action potential of a cardiomyocyte has several phases and ion currents</ins>.]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Doordat aan elkaar grenzende hartspiercellen depolariseren</del>, <del style="font-weight: bold; text-decoration: none;">ontstaat er een soort </del>domino<del style="font-weight: bold; text-decoration: none;">-</del>effect in <del style="font-weight: bold; text-decoration: none;">de vorm van een depolarisatiegolf</del>. <del style="font-weight: bold; text-decoration: none;">Deze depolarisatiegolf wordt geregistreerd op het </del>ECG.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">As adjacent cardiomyocytes depolarize</ins>, <ins style="font-weight: bold; text-decoration: none;">a </ins>domino effect <ins style="font-weight: bold; text-decoration: none;">is set </ins>in <ins style="font-weight: bold; text-decoration: none;">motion: the depolarization wave</ins>. <ins style="font-weight: bold; text-decoration: none;">This depolarization wave is registered on the </ins>ECG.</div></td></tr>
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Drj
https://en.ecgpedia.org/index.php?title=Action_potential&diff=8333&oldid=prev
Drj: /* Een Actiepotentiaal */
2008-09-07T21:24:48Z
<p><span dir="auto"><span class="autocomment">Een Actiepotentiaal</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 21:24, 7 September 2008</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*'''Fase 3''', De kalium efflux overschrijdt de calcium influx. De membraanpotentiaal herstelt zich weer tot 90mV (repolarisatie).</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*'''Fase 3''', De kalium efflux overschrijdt de calcium influx. De membraanpotentiaal herstelt zich weer tot 90mV (repolarisatie).</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[<del style="font-weight: bold; text-decoration: none;">Afbeelding</del>:actionpotential.png|thumb|De actiepotentiaal van een cardiomyocyt kent verschillende fasen en bijbehordende ionstromen.]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[<ins style="font-weight: bold; text-decoration: none;">Image</ins>:actionpotential.png|thumb|De actiepotentiaal van een cardiomyocyt kent verschillende fasen en bijbehordende ionstromen.]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Doordat aan elkaar grenzende hartspiercellen depolariseren, ontstaat er een soort domino-effect in de vorm van een depolarisatiegolf. Deze depolarisatiegolf wordt geregistreerd op het ECG.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Doordat aan elkaar grenzende hartspiercellen depolariseren, ontstaat er een soort domino-effect in de vorm van een depolarisatiegolf. Deze depolarisatiegolf wordt geregistreerd op het ECG.</div></td></tr>
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Drj
https://en.ecgpedia.org/index.php?title=Action_potential&diff=8332&oldid=prev
85.144.210.221: New page: == Een Actiepotentiaal == Een individuele hartcel spant zich aan wanneer er calcium-ionen naar binnen stromen. Maar deze calcium-ionen moeten ook weer naar buiten, anders zou de cel aanges...
2008-09-07T21:24:27Z
<p>New page: == Een Actiepotentiaal == Een individuele hartcel spant zich aan wanneer er calcium-ionen naar binnen stromen. Maar deze calcium-ionen moeten ook weer naar buiten, anders zou de cel aanges...</p>
<p><b>New page</b></p><div>== Een Actiepotentiaal ==<br />
Een individuele hartcel spant zich aan wanneer er calcium-ionen naar binnen stromen. Maar deze calcium-ionen moeten ook weer naar buiten, anders zou de cel aangespannen blijven. Iedere hartslag opnieuw worden er ionen naar binnen gelaten en weer naar buiten gepompt door ion-kanalen op de hartspiercel.<br />
<br />
Dit proces wordt in gang gezet door een doorgegeven electrisch signaal van de naburige cellen. Als reactie hierop, depolariseert de hartcel. Hierbij maakt hij ook zelf een electrisch signaal, de actiepotentiaal.<br />
<br />
Deze actiepotentiaal bestaat uit een aantal fasen;<br />
*'''Fase 4''', ook wel de rustfase. Het membraanpotentiaal; -90mV<br />
*'''Fase 0''', Snelle natrium kanalen worden geopend en natrium stroomt de cel in (depolarisatie). Dit zorgt voor de snelle upstroke.<br />
*'''Fase 1''', Kalium stroomt de cel uit (efflux) wat ervoor zorgt dat het membraanpotentiaal zichzelf herstelt naar 0mV<br />
*'''Fase 2''', ook wel de plateaufase Deze fase wordt gekenmerkt door kalium efflux en calicium influx (de cel in).<br />
*'''Fase 3''', De kalium efflux overschrijdt de calcium influx. De membraanpotentiaal herstelt zich weer tot 90mV (repolarisatie).<br />
<br />
[[Afbeelding:actionpotential.png|thumb|De actiepotentiaal van een cardiomyocyt kent verschillende fasen en bijbehordende ionstromen.]]<br />
<br />
Doordat aan elkaar grenzende hartspiercellen depolariseren, ontstaat er een soort domino-effect in de vorm van een depolarisatiegolf. Deze depolarisatiegolf wordt geregistreerd op het ECG.</div>
85.144.210.221